Many studies have been done on the benefits of Resveratrol over the years, but, most have focused on the effects in mice. However, studies with humans are becoming more prevalent. Anti-aging has been at the top of the list of benefits when it comes to resveratrol but there are many other benefits still being continually uncovered.
Clinical Trials With Diabetes
One area of study involves the benefits of resveratrol on diabetes. This research published in the European Endocrinology journal indicates that the supplement could have some benefits among which may increase the effects of the drug metformin, a well known drug used to treat Type 2 diabetes. An examination of this review by a Nutraingredients.com article, reported another study through clinical trials at Albert Einstein’s College of Medicine in New York, between 2005 and 2014.
The findings included that in people with Type 2 diabetes taking Resveratrol, were found to have an increase in insulin sensitivity as well as lower glucose levels. This was in comparison to those just taking the drug metformin on its own. These trials also investigated the effects of resveratrol on diabetes using a 500 milligram dose of the supplement in which was found the slowing of the progression of prediabetes into full blown Type 2.
In a separate study, patients with Type 2 diabetes, were given 250 mg of the supplement for 3 months. All of the participants received their normal oral medication but half of them received resveratrol. The results showed improved hemoglobin A1c, systolic blood pressure, total cholesterol and protein.
Heart Health and Resveratrol
In a study involving 40 patients who had experienced a heart attack, part of the group received 10mg of resveratrol daily for 3 months. The results showed that the Resveratrol improved ventricular diastolic and endothelial (lining of the arteries) function. They also experienced decreased LDL cholesterol. Another study of those at high risk for cardiovascular disease, revealed that their high urinary levels of resveratrol metabolites were connected to improvements in heart rate, HDL cholesterol triglycerides.
In line with the benefits to the arteries, an Australian study of post menopausal women and hypertensive overweight men, studied the effect of resveratrol on the brachial artery (located in the upper arm), which supplies blood to the tricep muscles. Defective blood flow in this vessel is connected to risks of obesity and hypertension. After being given a bioactive form of resveratrol, the subjects exhibited a compelling increase of blood flow within the hour.
Among the trials conducted with resveratrol, some involve the brain and dementia Alzheimers, Parkinson’s Disease and cancer. Studies have been conducted on the effect of resveratrol on short term memory. Daily doses of 200 mg of resveratrol were administered to overweight but healthy older adults over 6 months. This reportedly holds promise in an improvement in the functioning of the hippocampus, which is associated with memory.
In all the above mentioned trials, more conclusive evidence is continually sought especially in the levels of resveratrol needed in a human body to effectively improve a variety of health challenges.